The delivery challenge is posed by the blood–brain barrier (BBB), which prevents around 95% of small molecules, and almost all therapeutic biologics, from leaving the bloodstream and entering ...
The blood–brain barrier (BBB) is meant to protect the brain from noxious agents; however, it also significantly hinders the delivery of therapeutics to the brain. Several strategies have been ...
meaning the blood-brain barrier starts to be leaky. HAMILTON: That leaky barrier makes the brain more susceptible to infections and less able to remove waste products. The damage also leads to ...