Current lentiviral vector systems (the third generation) generate virus particles using four plasmids and a producer cell line. The rationale behind four plasmids is to enhance safety, as ...

The popularity of viral vector-based gene therapies and vaccines is rapidly growing ... Download this application note from Thermo Fisher Scientific to learn how scientists have used their lentiviral ...

As the particles are often pseudotyped with the envelope of the vesicular stomatitis virus (VSV), the vector can serve to introduce genes into a broad range of tissues and can be used in vivo.