Antiarrhythmic drugs act on the electrical ... 2020;2a] cardiac sodium channel blockers which shorten the action potential. Lidocaine is used intravenously to treat VT and VF.

produced plasma lidocaine concentrations that remained well below those that typically produce antiarrhythmic effects or toxicity. Mild application-site erythema occurred in most patients ...

The pharmacological treatment of VF/pulseless VT is of secondary importance to early defibrillation. Administration of antiarrhythmic drugs is considered in cases of refractory VF/pulseless VT—that is ...