Stefano Piccolo and colleagues now show that the tumour-suppressor protein p53 links receptor Tyr kinase (RTK)–Ras–mitogen-activated protein kinase (MAPK) signalling and transforming growth ...

The G1–G7 molecular subgroup classification based on the MAPK pathway activa-tion has offered for the first time a non-redundant ... Prior history of cancer, midline location or multifocality, ...