A previous report showed that induction of apoptosis in myeloma cells by bortezomib requires upregulation of NOXA via an MYC-dependent mechanism. 28 In addition, in T-cell lymphoma, bortezomib can ...

This breakthrough is expected to give rise to novel therapies against aggressive forms of cancer, such as Burkitt’s lymphoma (BL). More prevalent in Africa than in the United States and Western ...