Management. Treatment with prednisone 60 mg per day and methotrexate 15 mg per week was started, but symptoms worsened. Methotrexate was replaced by pulsed intravenous methylprednisolone (1 g ...

However, patients were excluded if they had discontinued therapy with ≥15 mg per week methotrexate owing to an inadequate response or toxic effects. Although the investigators acknowledge the ...

co-administered with weekly oral methotrexate 15 mg. "These data add to the growing body of evidence for UPLIZNA and KRYSTEXXA and strengthen our commitment to developing new treatment options for ...

The patients were randomized into one group of 40 who continued to receive intramuscular methotrexate 15 mg/wk and another group of 36 who were treated in a double-blind fashion with placebo ...

A combination therapy consisting of adalimumab (40 mg every 2 weeks), methotrexate (15 mg weekly) and a cyclo-oxygenase-2 inhibitor (rofecoxib 25 mg daily until July 2004, etoricoxib 90 mg daily ...