As gene expression profiling reaches a plateau and begins to face limitations, miRNA signature is a rising star that may provide new resolutions to old problems. It is difficult to say whether ...
But a study published November 9 in ACS Central Science finds that microRNAs (miRNAs) can also amplify gene expression. “It changes the landscape of microRNA,” Lara Mahal, a chemist at the University ...
Such gene signatures, however ... Most commercially available technologies for global miRNA expression profiling are based on DNA microarrays, in which the probes are spotted onto a glass surface.
MicroRNA(miRNA) are short non-coding single stranded RNA molecules that regulate gene expression at the post transcriptional level. They are known to play a critical role in multiple biological ...
miRNAs are important negative gene regulators that have critical roles ... The evaluated study examined the miRNA profiles in peripheral blood mononuclear cells from PDAC patients.
The researchers demonstrated that measuring microRNA ... single gene can be regulated by multiple microRNAs, and a single microRNA can impact numerous genes. The study investigates the expression ...