The bioenergetic deficits observed in Amyotrophic Lateral Sclerosis result from the disruption of mitochondria-associated ER membranes. Here, the authors show that this disruption impairs the use ...

The interest of major pharmaceutical companies for RMT based drug delivery to the CNS is gaining momentum: to-BBB has recently signed partnerships with a number of major pharmaceutical companies ...

In some cases, an inability to balance is referred to as a symptom known as ataxia. But ataxia can also be its own condition ...

Aging can play a major role as well ... As a stand-alone condition, "ataxia is a degenerative disease of the nervous system," explains Andrew Rosen, chief executive officer of the National ...

Lipids are the most abundant organic compounds found in the brain and the main component of plasma membranes of nervous cells ... Our team aims to understand the way lipids modulate proteins and ...

Researchers from Harvard University have made a significant breakthrough in understanding multiple sclerosis (MS), a chronic disease that affects the central nervous system and impacts nearly 2.8 ...

Fosigotifator is under clinical development by Calico Life Sciences and currently in Phase II for Unspecified Central Nervous System Disorders.

Researchers in Tokyo have broken ground in a gene therapy delivery method for diseases of the brain and central nervous system, and regenerative medicine for the intestinal tract. For more than a ...