This resulted in a very pure population of radial glial cells that functioned ... to genetically modify mouse ES cells, being able to obtain pure cultures of neurons from these cells will enable ...
Somewhat later in development, pyramidal neurons, the projection cells of the cerebral cortex, use radial glial processes as a scaffold to move away from the same proliferative zone and form the ...
Stationed within the meninges, squads of immune cells lie in wait, ready to unleash an inflammatory assault within the brain if needed. Holding these trigger-happy troops back during peacetime falls ...
It has been convincingly demonstrated by numerous studies that radial glial cells are neural stem cells. However, the processes by which neurons arise from radial glia and migrate to their final ...
Neurons may get all the glory, but they would be nothing without glial cells. While brain cells do the heavy lifting in the nervous system , it's the glia that provide nutrients, clean up waste ...
Researchers at the Max Planck Institute (MPI) for Multidisciplinary Sciences have now shown that, in addition to neurons, special glial cells in the brain also produce amyloid beta. This finding ...
Mujtaba T., Rao M.S., Fischer I. (2002). Grafted lineage-restricted neuronal precursors generate mature neurons in the adult spinal cord. Exp Neurol 177:360-375. Hormigo A, McCarthy M, Nothias JM, ...
The team then ran the same test on ferrets, the brains of which more closely resemble a primate’s because they have folds and “have more basal radial glia to start with,” she adds. Once again, the ...
The team (PhD students Harun Noristani, Markel Olabarria Larizgoitia and Chia-Yu Yeh) is now seeking further funding so they can test the use of growth factors on glial cells and explore a range of ...
the possibility that viruses such as SARS-CoV-2 could infect neurons or glial cells in our brain is less well documented, with reports that show contradictory results. Up to one third of COVID-19 ...
AskBio's approach meanwhile will involve using an adeno-associated virus (AAV) vector to deliver a gene for human glial cell line-derived neurotrophic factor (GDNF) into the neurons in the putamen.