In the late 1970s, the discovery that acyclic nucleoside analogues ... to the active metabolite by an HSV-encoded thymidine kinase — was unexpected, but the potential for exploiting viral ...

We are particularly interested in the genetic and posttranslational regulation of key molecules involved in intracellular calcium handling, including the ryanodine receptor type 2 (RyR2), striated ...

Trethera Corporation (“Trethera”), a clinical stage biopharmaceutical company committed to developing novel drugs targeting ...

Over the past few years my interests have expanded into understanding the role of CFTR-associated proteins in neutrophil function and inflammation. Application of stable analogues of phosphohistidine ...

Breakthrough Therapy designation Doravirine/islatravir (Merck) Combination of a non-nucleoside reverse transcriptase ... Brain-penetant Bruton tyrosine kinase inhibitor Treatment of adults with ...