"Nucleoside analogs are among the most important molecules to the advancement of modern medicine," says Michael Meanwell, assistant professor in the Department of Chemistry and corresponding ...

Antiviral nucleoside analogues and prodrug strategies are crucial in the development of effective treatments for viral infections. Nucleoside analogues mimic the building blocks of DNA and RNA ...

Nucleoside phosphorylases are enzymes that play a crucial role in the synthesis of nucleoside analogues, which are important compounds in the development of antiviral and anticancer drugs.

In addition, some nucleoside analogue reverse transcriptase inhibitors (most notably zalcitabine and stavudine and, to a lesser extent, didanosine) represent an important contributor to peripheral ...

This combination regimen, added to these patients receiving ongoing nucleoside analogue therapy, showed that a good amount of them achieved a functional cure. I will be going over this data below ...

Lactic acidosis is a rare but often fatal complication reported in some human immunodeficiency virus (HIV)-infected patients treated with nucleoside-analogue reverse-transcriptase inhibitors.