The chromatin landscape is a key aspect of epigenetic regulation in eukaryotes. Old histones are recycled during DNA replication, therefore providing a blueprint for the duplication of their ...

In addition to shelterin, telomeric DNA is also wrapped around histone octamers in a closed, heterochromatic state that compacts telomeric DNA and represses transcription at the chromosome end (Tardat ...

Jude team observed open chromatin regions in Müller glia ... it doesn't have access to the appropriate genes because of closed chromatin," explained first author Jackie Norrie, Ph.D., a scientist ...