A report published in PLoS Biology provides evidence that PTEN-induced putative kinase 1 (PINK1) is involved in selective autophagy of dysfunctional mitochondria. Recessive mutations in the PINK1 ...

Mutations in the PINK1 gene are the second most frequent cause of autosomal recessive parkinsonism after Parkin, and can represent a risk factor towards sporadic Parkinson's disease. The PINK1 ...