The study included a total of 65 patients with PACC. The median age at diagnosis was 66 years. Almost half of the patients (48%) presented with resectable/borderline-resectable disease (n = 28).

Microscopic image of the pancreas organoid. The magenta shows the cell nuclei, and the cyan highlights the acinar cells that secrete digestive enzymes. Researchers from the Organoid group ...

They found atrophic acinar cells interspersed with clumps of centroacinar cells lined all portions of the pancreas without evidence of ductular proliferation. Ectatic lumina contained loosely ...

This organoid contains the three main types of pancreas cells: acinar cells, ductal cells, and endocrine cells. Each of these cells plays a vital role. Acinar cells release enzymes that help break ...

Pancreatic ductal adenocarcinoma (PDAC) develops in the exocrine compartment of the pancreas, which is comprised of ductal and acinar cells. PDAC is associated with two major types of asymptomatic ...

NKX2.2 not detected in pancreatic progenitors before endocrine commitment Differentiation of the acinar lineage Nkx6.1 excluded from tip cells by e14.5 (CS19–20) (13) NKX6.1 still detected in ...

Proteomic studies of the pancreatic juice ... studies represent the major tasks for future investigations. L: Acinar lumen; ZG: Zymogen granule. (C–E) reproduced from [11] with permission ...