Ifosfamide-containing chemotherapy in Ewing's sarcoma: The Second United Kingdom Children's Cancer Study Group and the Medical Research Council Ewing's Tumor Study. J. Clin. Oncol. 16, 3628–3633 ...

Ewing sarcoma is caused by the abnormal fusion of two genes, which results in an oncogene. The protein produced by this oncogene causes the expression of genes that promote tumor development.

Fusion oncoproteins, such as those that cause the rare cancer Ewing sarcoma, are promising targets ... a geneticist studying the causes and consequences of genomic damage.