引言阿尔茨海默病(Alzheimer’s Disease, AD)的典型神经病理学特征之一,是tau蛋白异常磷酸化形成的神经原纤维缠结(neurofibrillary tangles, ...

New serine biomarkers show promise for early Alzheimer's detection, linking tau assemblies to cognitive decline and offering ...

A complementary drug to combat Alzheimer’s disease could target a specific part of the nerve cell protein tau.

Years before tau tangles show up in brain scans of patients with Alzheimer's disease, a biomarker test developed at the ...

近日，罗氏诊断阿尔茨海默病脑脊液系列试剂盒（包括Elecsys ® β-Amyloid (1-42) CSF II、Elecsys ® Phospho-Tau (181P) CSF、Elecsys ® Total-Tau CSF检测试剂，以及 ...

Years before tau tangles show up in brain scans of patients with Alzheimer's disease, a biomarker test developed at the ...

Researchers say CSF biomarker test correlates with the severity of cognitive decline, independent of other factors, including brain amyloid deposition.

“We can profile neurons with different phospho-tau profiles and where they are located in the tissue to learn how they interact with their environment,” says Orr. It's another step towards ...

​近日，国家药监局器审中心发布医疗器械优先审批申请审核结果公示（2025年第1号），Roche Diagnostics GmbH（罗氏诊断公司，以下简称：罗氏诊断）的6款AD检测产品——总Tau蛋白脑脊液质控品、 磷酸化tau-181蛋白脑脊液质控品、β淀粉样蛋白1-42（Aβ1-42）脑脊液质控品、β淀粉样蛋白1-42（Aβ1-42）脑脊液定标液、磷酸化tau-181蛋白脑脊液定标液、总Tau蛋 ...

This Review summarizes our current understanding of the mechanisms of tau-mediated neurodegeneration in Alzheimer's disease and related disorders. It is believed that tau-mediated ...

Years before tau tangles show up in brain scans of patients with Alzheimer's disease, a biomarker test can detect small amounts of the clumping-prone tau protein and its misfolded pathological forms ...