In this issue, Gishizky and coworkers describe yet another use for phage display—a method for mapping protein–protein interactions that is faster than two-hybrid systems and that allows the ...

The same kind of protein could appear in multiple compartments ... In the end, the team generated a map that organizes proteins according to their relationships with one another — a high ...

This image shows the mapping of protein 3D shapes. Each dot represents a protein shape. The distance of proteins in the map represents similarity of their shapes. Disclaimer: AAAS and EurekAlert!

The work demonstrates a transformative step forward in profiling protein expression across whole, dense tissues. “Conventionally, investigating the molecules within cells requires dissociating ...

"We've created the first large-scale map to visualize the impact of mutations on protein localization within the cell," said Mikko Taipale, co-principal investigator on the study and professor of ...

For the study, the team developed a protocol for enriching brain endothelial cells in mice, which makes it possible to resolve age-related changes in protein composition. Using an unsupervised ...

A multi-institutional team of researchers has created a new and improved genetic map for the laboratory rat ... the addition of more than 1,100 new protein-coding genes that were previously ...