Figure 1: Plots of isotropic B factors calculated for protein structures solved in both the native and methylated states. We showed in this large-scale study that reductive methylation of proteins ...

Protein methylation is a type of post-translational modification featuring the addition of methyl groups to proteins. It can occur on the nitrogen-containing side-chains of arginine and lysine, but ...

This important work advances our understanding of DNA methylation and its consequences for susceptibility to DNA damage. This work presents evidence that DNA methylation can accentuate the genomic ...

Genes make up the blueprints and outline the process of building every living organism.To ensure that the right genes are ...

Researchers developed MethylGPT, a powerful transformer-based model that identifies DNA methylation patterns, enabling ...