In contrast, using DNA shuffling 23 to make protein variants creates mosaic proteins that contain fragments from different starting proteins. Although screening identifies which of these variants ...

Using saturation mutagenesis and DNA shuffling to vary the protein residues around the biliverdin chromophore, Shu, Tsien and their colleagues evolved a bright, photostable and monomeric infrared ...

The researchers are continuing to look for other examples of telltale protein shuffling, both in other viral infections and in Alzheimer's disease. "We think our Organelle Profiling method could ...