Point mutations in genes encoding coagulation factor V and prothrombin have been previously associated with thrombophilia. In the 5 October issue of The New England Journal of Medicine ...
Thirteen patients with liver disease and an abnormal prothrombin time refractory to vitamin K therapy were studied (Tables 1 and 2). None of the patients were actively bleeding, and none had ...
[9] Pregnant women with the most common heritable thrombophilias (i.e., heterozygosity for factor V Leiden [OR: 8.3; 95% CI: 5.4–12.7] or the prothrombin G20210A mutation [OR: 6.8; 95% CI ...