Purine analogues, such as fludarabine and cladribine, are used in the treatment of certain types of cancer, particularly hematological malignancies. These compounds interfere with DNA synthesis and ...

Gout is a painful form of arthritis caused by the buildup of excess uric acid, which forms crystals in the joints. This condition leads to sudden pain, swelling, and inflammation, most commonly ...

A low purine diet typically centers around fruits, vegetables, and whole grains. It also minimizes the consumption of red meat, seafood, and alcohol. Healthcare professionals often recommend a low ...

The purine content of different parts also varies, ranging from low to very high. If you have gout and hyperuricemia, it's important to consider the types and amounts of purines you take in. One of ...

The purine/purinergic system has emerged as a fundamental regulator of cellular communication ... Investigate how purinergic signaling modulates insulin sensitivity, glucose homeostasis, and the ...

If you’ve experienced the horrible pain of a gout attack, you surely don’t want it to happen again. Your doctor may recommend getting your serum uric acid (SUA) level below 6 mg/dL by changing your ...