Autophagy was originally viewed as a bulk degradation process. However, certain pathogens, aggregated proteins, damaged mitochondria and even ribosomes can be selectively degraded by autophagy.

Autophagy is a natural regeneration process that occurs at a cellular level in the body, reducing the likelihood of contracting some diseases as well as prolonging lifespan. In 2016, Japanese ...

My group focuses on understanding cell signaling pathways primarily linked with the ubiquitin and autophagy systems and frequently altered in diseases, including neurodegenerative disease. To this end ...