A new study highlighting the importance of a large protein complex called the exocyst in cell growth, division and ...

Synaptic vesicle docking and fusion are mediated by the assembly of a stable SNARE core complex of proteins, which include the synaptic vesicle membrane protein VAMP/synaptobrevin and the ...

Our group focuses on two assembly pathways: adaptor protein assembly during vesicle budding and SNARE complex assembly during vesicle fusion. We aim to use findings from these two model pathways to ...

The chaperone Hsc70 (green) helps keep SNAP-25 in the proper shape so that it can help form the SNARE complex, enabling neurotransmission. AMHERST, Mass. – A team of researchers from the ...

"I work on a specific protein called SNAP-25," says Bhasne. "Without SNAP-25, the SNARE complex, which is responsible for guiding the synaptic vesicle to the right docking points on the ...

"I work on a specific protein called SNAP-25," says Bhasne. "Without SNAP-25, the SNARE complex, which is responsible for guiding the synaptic vesicle to the right docking points on the ...