THE fundamental defect of sickle-cell disease is a mutation that leads to substitution ... At 9 months of age he appeared pale. Anemia was found, and electrophoresis established the diagnosis ...

Children with sickle cell anemia are vulnerable to serious infections ... sickle-cell disease in which there is homozygosity for the mutation that causes HbS. Sickle-cell anaemia is also referred ...

Sickle cell anemia refers to a group of genetic blood disorders that affect a person’s levels of hemoglobin, the protein in red blood cells that transports oxygen. Sickle cell anemia causes a ...

Many individuals with sickle cell anemia undergoing controlled ovarian ... cell disease in which there is homozygosity for the mutation that causes HbS. Sickle-cell anaemia is also referred ...

The sister of a"caring and selfless” dad whose life was tragically cut short of Christmas Day after a long battle with sickle ...

It is a potential game changer for young sickle cell patients because the therapy eliminates the need for a suitable donor and removes the mutation for a life free of sickle cell disease." ...

Up to 30% of patients with AML have a specific mutation called FLT-3 ... Study: Bone mass declines with age for patients with sickle cell disease Sickle cell disease, a blood disorder that ...

Living with Sickle Cell Disease means that every treatment comes with its own side effects. Today, we will focus on the dangers of blood exchange or transfusion and the risk of iron overload.

The European Commission has granted orphan drug status to mitapivat, an oral investigational therapy for sickle cell disease.