This genetic blood disorder can trigger a host of health issues, some of which can be life-threatening. Learn more about what ...

The hallmark symptom of sickle cell anemia is pain, particularly episodes of sudden pain, sometimes called sickle cell crises ...

Both normal RBCs and sickle cells experience repeated cycles of hypoxia and mechanical fatigue. To investigate the impact of these challenges on RBC damage and degradation accumulation, we developed ...

SAN DIEGO -- Treatment with hydroxyurea led to more hematologic dose-limiting toxicities (DLTs) compared with placebo in ...

The cells' sickle shape and associated fragility result in rapid RBC destruction by a patient's own body. This leads to leads to anemia, as well as congestion and fibrosis of the spleen at an ...

THE fundamental defect of sickle-cell disease is a mutation that leads ... below the right costal margin, but the spleen was not palpable. An electrovectorcardiogram showed marked hypertrophy ...

The disease gets its name because when you have SCD, your red blood cells look like a sickle, which is a C-shaped farm tool. Normal red blood cells are round and pliable. With sickle cell ...

Sep. 12, 2024 — Researchers have found that being a carrier for sickle cell disease, known as having sickle cell trait, increases the risk of blood clots, a risk that is the same among diverse ...

Jimi Olaghere thought he would have to wait decades to be freed from his sickle cell disease - but now scientists have engineered his blood to overcome the disease which left him in constant pain.