Choanoflagellate Sox genes have traits similar to those found in mammalian Sox2 genes. In mice, Sox2 interacts with a POU member called Oct4; but choanoflagellate POU genes are incapable of ...

Ralf Jauch's lab in The University of Hong Kong / Center for Translational Stem Cell Biology, the team introduced choanoflagellate Sox genes into mouse cells, replacing the native Sox2 gene ...

including a Sox (Sox2) and a POU (Oct4) gene. In this new research, through a set of experiments conducted in collaboration with Dr Ralf Jauch’s lab in The University of Hong Kong / Centre for ...