We still do not understand how alternative splicing is regulated, but the following fact is now quite clear: in metazoans, it happens very often. Computational analysis of expressed sequences can ...

A large-scale effort to identify sequences involved in silencing exon and splice site usage sheds some new light on the properties of these poorly understood motifs and demonstrates the potential ...

Compared to the state-of-the-art "SpliceAI" tool, the Hopkins team's "Splam" method uses a much shorter DNA sequence window to predict RNA splice sites, making its model more biologically realistic ...

Novel paradigm for therapeutics based on RNA splicing modulationLead program in Huntington’s diseaseDenmark – Odense – 07/01/2025 – Inverna ...

Compared to the state-of-the-art "SpliceAI" tool, the Hopkins team's Splam method uses a much shorter DNA sequence window to predict RNA splice sites, making its model more biologically realistic ...