The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion. While healthy transthyretin moves hormones through blood and spinal fluid, misfolded ...

The CNS is the brain and spinal cord. Muscles contracting or glands secreting hormones are the response of effectors coordinated by the CNS. Receptors are groups of specialised cells. They detect ...

Insights into the structures could lead to improved treatment strategies for transthyretin amyloidosis, a progressive, fatal disease in men.

“The new structures reveal differences in two thyroid hormone binding sites previously ... “The conformational landscape of human transthyretin revealed by cryo-EM,” are Karina Nugroho ...