such as BCL-2, TNF, NF-κB and p53. This interest in part stems from the substantial potential to therapeutically intervene in these pathways, as highlighted in this issue. However, despite ...

AIF = Apoptosis-inducing factor; APAF-1 = Apoptotic protease activating factor-1; Bak = Bcl-2 antagonist/killer; Bax = Bcl2-associated ... TRAIL = TNF-related apoptosis-inducing ligand.