One of the genes consistently upregulated was thioredoxin-interacting protein, which has been linked to neuronal cell death. "Each of these 11 genes exhibited consistent regulation across all PFAS ...

The high-resolution structure of an oxidoreductase from the archaeon Pyrococcus furiosus shows that it comprises two adjacent domains each with the thioredoxin (trx/grx) fold. Its functional ...

We recently identified thioredoxin-interacting protein (TXNIP) as an attractive target in this regard. Glucose and diabetes upregulate β-cell TXNIP expression, and TXNIP overexpression induces β ...

A research team led by Prof. QIN Guozheng from the Institute of Botany of the Chinese Academy of Sciences has unveiled a previously unrecognized mechanism by which the RNA N6–methyladenosine (m6A) ...

A study uncovers how H2O2-induced redox modification regulates the RNA demethylase SlALKBH2. This modification stabilizes SlALKBH2 and accelerates tomato ripening without altering its m6A demethylase ...