Two recent identically designed, randomized, placebo-controlled, multicenter studies investigated the effects of tolvaptan, an oral vasopressin V 2-receptor antagonist, on hyponatremia.

Expert Rev Cardiovasc Ther. 2008;6(5):601-608. The first Phase III clinical trial to study tolvaptan was the Study of Ascending Levels of Tolvaptan in Hyponatremia (SALT)-1/-2, which consisted of ...

Vasopressin is elevated in both acute and chronic heart failure, and may lead to volume retention, worsening heart failure and hyponatremia. Tolvaptan, a selective vasopressin antagonist has been ...

Novak received a letter from BCBSKS stating that a “consultant’s review of all available information has determined the ...

New Delhi: Considering the published data on efficacy studies of Tolvaptan Tablets 7.5 mg, the Subject Expert Committee (SEC) ...

Get detailed information on Tolvaptan, including pronunciation, uses, dosage guidelines, indications, and instructions on how and when to take it and when to avoid it. The updated prescription ...

Novak received a letter from BCBSKS stating that a “consultant’s review of all available information has determined the denial of Tolvaptan for the treatment of Hyponatremia is upheld.” ...