In a study published in Nature Structural and Molecular Biology, scientists from the Department of Medical Biochemistry and ...

In a groundbreaking study, scientists from Karolinska Institutet discovered that water molecules are crucial in helping transcription factors, proteins that regulate gene activity, read the human ...

which are obscured by averaging across all the molecules present in an ensemble. We are interested in understanding the mechanisms governing interactions between proteins that are important for ...

In a recently published study in Nature Structural and Molecular Biology, scientists from the Department of Medical ...

“Our Lego-block-like design allows us to tack different small molecules together to control gene transcription in different ways. It is the beginning of a whole new class of GeneTAC molecules.

The genetic information stored in DNA is a living archive of instructions that cells use to accomplish the functions of life. Inside each cell, catalysts seek out the appropriate information from ...

Protein synthesis is vital for life, translating genetic information from DNA to functional proteins through transcription ...

the researchers focused on the interaction between two molecules, NORAD and STAT3, which are key players in genetic processes. NORAD is a unique RNA molecule that plays vital roles in genetic ...

coli, a simple model organism, to map how metabolites—small molecules essential for life—interact with key proteins such as enzymes and transcription factors. These interactions control ...

can promote transcription at telomeres.” Telomeres were thought to be transcriptionally silent until several years ago when researchers found that mammalian telomeres, including human ones, are ...

This transfer of life's code from DNA to RNA is called transcription. Next, a ribosome uses the message encoded in RNA to build proteins—the molecules performing most of the essential functions ...