Kinesin with vesicle is attached with two "feet" to the cell's microtubule. This is a safe and stable time period. The kinesin untethers its back foot and moves it forward. This is a vulnerable ...

Cargo-bearing vesicles pinch off of one set of membranes and travel along microtubule tracks to the next set of membranes, where they fuse with these structures. Trafficking occurs in both ...

Targeting dynein to microtubule plus ends ... late endosomes or trans-Golgi vesicles), and their GTPase state and thus conformation is linked to the life cycle and direction of trafficking ...