T cells use the T cell antigen-receptor (TCR) to recognize their antigens, which are often in the form of peptides bound to major histocompatibility complex molecules (MHC), also called HLA (human ...

An intracellular sensor that tracks the quality of so-called MHC-I molecules which aid the immune system in identifying and eliminating dangerous cells, including tumor cells has been discovered ...

The TRACeR I platform was incorporated into a humanized antibody fragment in a bispecific T-cell engager (BiTE) format. When ...

Countless molecular "radio masts" - the MHC-I molecules - are responsible for presenting these fragments. They are assembled inside the cell and then transported to the membrane, the lipid layer ...

Findings published in Science Immunology resolve how human LAG-3 binds to its main ligand providing a better foundation for ...

Northwestern Medicine scientists have developed a method for identifying reactive cysteines on peptide antigens within the ...

Cancer immunotherapy has revolutionised treatment for patients, whereby the body’s own immune system is harnessed to destroy ...

Clinical-stage company Immutep (ASX:IMM) has announced new findings published in Science Immunology that resolve how human ...

Immutep (IMMP) announces new findings published in Science Immunology that resolve how human lymphocyte activation gene 3 binds to its main ...