You have full access to this article via your institution. There are several methods for removing MAPs from MTP to produce purified tubulin: using DEAE-Sephadex or phosphocellulose chromatography ...
XMAP215 functions as a processive polymerase... But how does XMAP215 promote the addition of so many tubulin dimers during its interaction with the microtubule end? Using negative-stain electron ...
The taxanes exert their cytotoxic effect by binding tubulin, stabilizing the microtubule and inhibiting its disassembly, ultimately leading to cell death by apoptosis. Although there is no maximum ...
Proteins containing disordered domains perform many important cellular functions. My lab currently has two main projects, one to dissect the role of tubulin's C-terminal tail in microtubule structure ...