Cancer-associated fibroblasts (CAFs ... Distinct subtypes with different roles in the tumor microenvironment Two of these subtypes have the ability to influence the immune system, but in different ...

Tumor cells transform fibroblasts into cancer-associated fibroblasts, which have an important immunosuppressive activity on which growth, invasion, and metastasis depend. These activated fibroblasts ...

Subscribe for FREE Cancer-associated fibroblasts (CAFs) are an important component in solid tumors ... Distinct subtypes with different roles in the tumor microenvironment Two of these subtypes have ...

The Mara Sherman lab aims to understand the heterocellular interactions among pancreatic cancer cells and their surrounding microenvironment, and to target these networks for therapeutic benefit. Our ...

More information: Agnes Forsthuber et al, Cancer-associated fibroblast subtypes modulate the tumor-immune microenvironment and are associated with skin cancer malignancy, Nature Communications (2024).

Cancer-associated fibroblast subtypes modulate the tumor immune microenvironment and are associated with the aggressiveness ...