inducing chirality in transformations of the substrate by noncovalent interactions between the catalyst microenvironment and ligand. Here, the authors demonstrate that the chiral-at-metal ...

which act as enzyme substrates or inhibitors, signaling molecules, allosteric modulators, structural anchors, etc. Monitoring protein-ligand interactions is thus essential for characterizing ...

Our research efforts are directed toward developing new classes of ancillary ligands (including now-commercialized ‘DalPhos’ ligands) and derived transition metal complexes that exhibit interesting ...