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乳腺癌耐药背后的“推手”——TMEM45A激活AKT/mTOR通路
【导读】帕博西尼(Palbociclib)是一种CDK4/6抑制剂,在治疗HR+乳腺癌中发挥着至关重要的作用。然而,palbociclib的耐药性是一个值得进一步研究的重大问题。团队的研究发现,TMEM45A是palbociclib耐药性的潜在驱动因 ...
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