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Vertex Announces US FDA Approval of ALYFTREK™, a Once-Daily Next-in-Class CFTR Modulator ...
See below for Important Safety Information, including a Boxed Warning. “ALYFTREK is our fifth CFTR modulator to secure FDA approval and represents another significant milestone in our journey to ...
The EMBO Journal4 天
Structural insights into binding-site access and ligand recognition by human ABCB1
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. ABCB1 is a broad-spectrum efflux pump central ...
腾讯网6 天
Immunity: ABCC1在感染和肿瘤免疫靶向研究中的新突破 | Cell Press论文速递
图2 hABCC1 的二聚化界面 冷冻电镜结构还揭示了hABCC1的核心结构，包括两个跨膜域（TMD1和TMD2）和两个核苷酸结合域（NBD1和NBD2）。在未结合底物时 ...