CRISPR-Cas systems are prokaryotic immune systems that confer resistance to foreign genetic elements such as plasmids and phages. CRISPR-Cas systems have been exploited for targeted genome editing ...

The management of Leishmania donova ni (LD), responsible for fatal visceral leishmaniasis (VL), faces increasing challenges due to rising drug-unresponsiveness, leading to increasing treatment ...

We apply our strategy to in silico biological network models of real systems to demonstrate its effectiveness. In the following, we give background information on the Boolean modeling framework and ...

Motor neurons (white) and a blood vessel (red), derived from the ALS patient’s stem cells, form functioning tissue, as revealed in this enlarged image (background). Photograph by CRAIG CUTLER ...

Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a family of multifunctional RNA-binding proteins able to process nuclear pre-mRNAs into mature mRNAs and regulate gene expression in ...