Maintaining cells in the quiescent G 0 phase of the cell division cycle is achieved by suppressing the expression of genes required for cell-cycle progression. In the May 10 Science, Hidesato Ogawa ...

Understanding the dynamics and stability of these marks through the cell cycle is crucial in maintaining a given chromatin state. Recent research has highlighted DNA methylation as a bona fide ...

Cell-cycle activation in quiescent cells is correlated with a change in chromatin structure and requires the activation of the retinoblastoma (RB)–E2F pathway. The gain of a new cell fate is ...