Do you know why Step Pharma is selectively targeting a key enzyme called cytidine triphosphate synthase 1 (CTPS1) for cancer? Watch this short video to learn why CTPS1 is regarded as cancer’s ...

Chemotherapy drugs can kill cancer cells by halting DNA replication, but a glucose-depleted environment can help cancer cells ...

Connecting decision makers to a dynamic network of information, people and ideas, Bloomberg quickly and accurately delivers business and financial information, news and insight around the world ...

Kalckar, H. M., and Cutolo, E., II e Congr. de Biochimie, 260 (1952).

Department of Pharmacy, Saarland University, Campus E8.1, Saarbrücken D-66123, Germany Department of Pharmacy, Saarland University, Campus E8.1, Saarbrücken D-66123, Germany Helmholtz Institute for ...

Future Neurology. 2012;7(2):193-207. A Phase IIb study randomized 257 patients to one of several dosing regimens of BG-12 or placebo for 24 weeks. [15] The study met its primary end point ...

These modifications occur at adenosine, uridine, and cytidine bases, providing specific structural and functional benefits. Figure 3. Key components involved in mRNA-LNP formulation. A typical LNP ...

ATP, an acronym for adenosine triphosphate, provides energy to our cells, thereby aiding in the execution of physical activities. During workout sessions, our bodies deplete ATP, therefore ...

By analogy, our group recently discovered that murine CAFs sequester large amounts of activated gemcitabine (2',2'-difluorodeoxycytidine-5'-triphosphate (dFdCTP)) intracellularly, preventing its ...