RNA sequencing refers to techniques used to determine the sequence of RNA molecules. It includes high-throughput shotgun sequencing of cDNA molecules obtained by reverse transcription from RNA ...

DNA sequencing is any chemical, enzymatic or technological procedure for determining the linear order of nucleotide bases in DNA. Sanger sequencing by replicative synthesis in the presence of ...

Changchun Genescience Pharmaceuticals Co. Ltd. has reported GSC-000829, a novel and selective FGFR2/FGFR3 inhibitor being developed for the potential treatment of cancer. BioWorld Science Conferences ...

CREATE SEQUENCE creates a new sequence number generator. This involves creating and initializing a new special single-row table with the name name. The generator will be owned by the user issuing the ...

The evidence for the authors' claims is convincing, combining state-of-the-art conditional gene deletion in the mouse lens with histological and molecular approaches. This work should be of great ...

TYRA-300 showed promising safety and preliminary antitumor activity in FGFR3-altered metastatic urothelial cancer, with a 54.5% partial response rate and 100% disease control in the SURF301 trial.

Vosoritide (BMN 111) 是一种改良的重组 CNP (C 型钠尿肽) 类似物，与 NPR-B (B 型钠尿肽受体) 结合并降低 FGFR3 (成纤维细胞生长因子受体 3) 的活性。Vosoritide ...

Advances the sequence object to its next value and returns that value. This is done atomically: even if multiple sessions execute nextval concurrently, each will safely receive a distinct sequence ...

Considering the occurrence of several actionable alterations including a TPM4:NTRK1 fusion reported herein, these results support the use of next-generation sequencing (NGS) including RNA analysis for ...

In this valuable study, the authors used an elegant genetic approach to delete EED at the post-neural crest induction stage. The usage of the single-cell RNA-seq analysis method is extremely suitable ...

Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge CB2 1EW, U.K.