For the experiments requiring medium adaptation, RPMI 1640 medium without L-glutamine (Life Technologies, Cat#: 21870076 ... 3.3 Rylaze treatment upregulates serine biosynthesis through the amino acid ...

Inhibiting GLS1 reduced high blood pressure in the right side of the heart of PAH rats and improved various measures of heart ...

Glutamine is deaminated to form glutamate, which is processed to produce a-KG for use in the TCA cycle. HIF-1 is a heterodimeric protein that could alter various genes coded for enzymes involved in ...

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A research group from Nagoya City University has elucidated the significance of birth in the maintenance of neural stem cells (NSCs).The findings of the study are published in Science Advances.

A new study has unveiled the intricate genetic mechanisms that regulate theanine accumulation in tea plants—a key determinant ...

Article subjects are automatically applied from the ACS Subject Taxonomy and describe the scientific concepts and themes of the article. Glutamine synthetase (GS) is an ancient enzyme present in all ...

We see the seven stones of the Molecular Systems Biology cover as a visual allegory for Aristotle's visionary thought: The whole is greater than the sum of its parts.

This study presents a useful finding that targeting amino acid metabolism can overcome Trastuzumab resistance in HER2+ breast cancer. The evidence supporting the claims of the authors is solid and the ...