T-cell therapy, originally developed for haematological malignancies, has recently emerged as a promising therapy for ...

Taken together these data highlight that innate immune mediators ... including the role of HIV signaling through TLRs and other pattern recognition receptors and how this affects pDC functions ...

This study aims to investigate the clinical relevance of Arp2/3 complex subunits, particularly ARPC1A, in pan-cancer, and to further analyze the potential biological mechanisms of ARPC1A, as well as ...

The Company continues to enroll people living with HIV (PLWH) in the multiple ascending dose (MAD ... KIMMTRAK is a novel bispecific protein comprised of a soluble T cell receptor fused to an anti-CD3 ...

or later stages of an HIV infection. Because your body’s immune system is trying to fight off the first infection from HIV, the response can cause a rash. If you already have HIV, you may have ...

HIV is a virus that damages cells in the immune system and disrupts the body's ability to fight off infections and diseases. If the immune system is severely damaged by HIV, the person can develop ...

Primary immune thrombocytopenia is an autoimmune disease in which autoreactive B cells play a crucial role in pathogenesis by producing autoantibodies primarily directed against platelet surface ...

A checkpoint receptor that often resides on the surface of immune system cells, the PD-1 molecule works as a type of "off" switch that keeps immune cells from attacking other cells. After its ...

A new drug is hugely effective at protecting people from HIV infection and needs to be injected only twice a year. Gilead Sciences, GSK, ViiV Healthcare 1 to 3 years In June 2024, results from a ...

A study conducted by researchers at the Kennedy Institute of Rheumatology has uncovered a pivotal role of asparagine metabolism in regulating B cell homeostasis and immune response. Germinal ...

Cell-to-cell spread can enable viruses to evade the humoral immune response ... that must engage more than one receptor to enter the cell (for example, HIV-1 (Ref. 1); Table 1).