Growth factor independence-1 (GFI1) is a crucial transcription factor that plays a significant role in hematopoiesis, the process by which blood cells are formed. Recent research has focused on ...

Together, these data suggest new regulatory roles for ARID3a. The genes influenced by ARID3a are likely to play pivotal roles in lineage decisions, highlighting the importance of this understudied ...

Through the activation and repression of the target genes, transcription factors (TFs) determine the fate of cells within tissues, organs and organisms, controlling the development. Most TFs act ...

From the Center for Systems Biology (W.C.P., M.N., F.K.S.), Massachusetts General Hospital and Harvard Medical School, Boston. From the Center for Systems Biology (W ...

Reply to: Automatic for the People: What Has Machine Learning Analysis of Positron Emission Tomography Left for the Physician? Clonal hematopoiesis (CH) has been associated with a variety of adverse ...

This valuable study presents a mouse gastruloid model that can be used to generate hematopoietic progenitors as well as leukemic cells. However, in its current form, the manuscript is inadequate ...

When looking for products to mitigate the physical signs of aging, experts recommend adding a growth factor serum to your routine. The powerful skincare cocktails often come with a hefty price tag ...

Up to 40%–50% of the cases of ACLF have no identifiable trigger; in the remaining patients, sepsis, active alcoholism and relapse of chronic viral hepatitis are the most common reported precipitating ...

Guido Marcucci, MD, Michael A. Caligiuri, MD, Clara D. Bloomfield, MD ...