But despite their limitations, patient-derived organoids may be more reflective of their tissue of origin than other in vitro models, and so offer exciting new opportunities. For example ...

Scientists grow organ-specific stem cells in vitro using 3D cell culture technology to produce organoids, miniature organ models that provide valuable insight into tissue development. Researchers ...

The development of organoids has greatly advanced in the last decade with the realization that two-dimensional cellular samples in vitro cannot mimic the behavior of an entire organ. Today ...

These investigations can be conducted in vitro using retinal organoids to quickly assess the retinal toxicity of novel compounds. Modeling retinal drug toxicity: Retinal organoids were tested for ...

Bone marrow contains a heterogeneous mixture of mature and maturing precursors of blood cells, progenitor cells for myeloid and lymphoid lineages, and hematopoietic and mesenchymal stem cells.

Their research findings, published in the journal Nature Materials, mark a shift toward in vitro ... donors or lymphoma patients are cultured in these gel-like environments, the organoids support ...

Researchers have developed lab-generated lymph node–like organoids that, when transplanted into mice in place of lymph nodes that have been removed, drain fluid and connect to the animals’ original ...

AAV vector evaluation in vitro for retinal gene therapy Retinal organoids from Newcells have demonstrated the ability to serve as an instructive in vitro model for assessing novel retinal gene ...

Newcells’ iPSC-derived retinal organoids offer a unique in vitro platform for disease modeling and investigating drug efficacy. These retinal organoids are fully stratified and present all of the ...