Pharmacokinetic studies of lacosamide in humans show that it is minimally bound to plasma proteins, has approximately a 13-h half-life, is excreted renally (as unchanged drug or metabolites ...

Idorsia Pharmaceuticals has claimed FDA approval for aprocitentan as a treatment for resistant hypertension, becoming the first drug in the endothelin receptor antagonist class for that indication.

Vimpat is UCB’s second-biggest drug after TNF inhibitor Cimzia (certolizumab pegol) which is also due to lose patent protection by 2024 and contributed €622 million out of total sales of €2. ...

The Centers for Disease Control and Prevention. U.S. Overdose Deaths Decrease in 2023, First Time Since 2018. National Institute on Drug Abuse. What classes of prescription drugs are commonly misused?

Drug delivery describes the method and approach to delivering drugs or pharmaceuticals and other xenobiotics to their site of action within an organism, with the goal of achieving a therapeutic ...

Paralytic drugs, or neuromuscular blocking agents (NMBAs), are powerful muscle relaxants used to prevent muscle movement during surgical procedures. They're also used during critical care, such as ...

A complex investigation into the supply of Class A drugs into Chesterfield and Sheffield began back in 2022. Almost 20kg of cocaine, a 9mm handgun, and approximately £1.2m in cash were recovered ...

Drug development describes the process of developing a new drug that effectively targets a specific weakness in a cell. This process involves specific pre-clinical development and testing ...

You might just know someone, close or distant, who has struggled with drug addiction at one point in time. It could be a distant relative or someone you went to school with, but the sheer probability ...

To overcome numerous health disorders, heterocyclic structures of synthetic or natural origin are utilized, and notably, the emergence of various side effects of existing drugs used for treatment or ...

Drugs under international control include amphetamine-type stimulants, coca/cocaine, cannabis, hallucinogens, opiates and sedative hypnotics. Countries have decided to control these drugs because they ...