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5 天
MGE 增强剂选择人类 ES 细胞产生的中间神经元前体
内侧神经节隆起(MGE)是一种胚胎前脑结构,产生大部分皮质中间神经元。将 MGE 移植到出生后中枢神经系统的特定区域可以改变回路功能,改善小鼠癫痫、帕金森病、疼痛和苯环己哌啶诱导的认知缺陷模型的缺陷。在此,我们描述了从小鼠胚胎干 (ES) 细胞生成 ...
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