The locus coeruleus is emerging as a major new area of research interest, with many important functions such as regulating ...

These processes are genetically controlled and depend both on the history of cells (lineage) and on the activities of signalling pathways, which coordinate the cell interactions leading to ...

Not revised: This Reviewed Preprint includes the authors’ original preprint (without revision), an eLife assessment, and public reviews. This study investigates the role of norepinephrine (NE) ...

Find out why stress can worsen allergy symptoms. Learn about the cellular chain reaction that occurs in the body and how it ...

7 refine our understanding of the signaling effects of oncogenic KRAS. Rather than activating multiple effectors, mutant KRAS signals preferentially through the RAF–MEK–ERK pathway ...

Filled with the top stories to start your day, and emergency news alerts.

By stashing the norepinephrine away ... This switch is known as the "Notch signaling pathway." By completely switching off the pathway and dramatically increasing the number of fibroblasts ...

The results for the first time describe the tightly synchronized oscillations in the neurotransmitter norepinephrine (NE), cerebral blood, and cerebrospinal fluid (CSF) that combine during non ...